The cell cycle and cancer worksheet

Take the Cell Biology Quiz Interphase: Interphase, which appears to the eye to be a resting stage between cell divisions, is actually a period of diverse activities. Those interphase activities are indispensible in making the next mitosis possible.

The cell cycle and cancer worksheet

Events during Mitosis Interphase: Cells may appear inactive during this stage, but they are quite the opposite. This is the longest period of the complete cell cycle during which DNA replicates, the centrioles divide, and proteins are actively produced.

During this first mitotic stage, the nucleolus fades and chromatin replicated DNA and associated proteins condenses into chromosomes. Each replicated chromosome comprises two chromatids, both with the same genetic information.

Microtubules of the cytoskeleton, responsible for cell shape, motility and attachment to other cells during interphase, disassemble. And the building blocks of these microtubules are used to grow the mitotic spindle from the region of the centrosomes.

In this stage the nuclear envelope breaks down so there is no longer a recognizable nucleus. Some mitotic spindle fibers elongate from the centrosomes and attach to kinetochores, protein bundles at the centromere region on the chromosomes where sister chromatids are joined.

Other spindle fibers elongate but instead of attaching to chromosomes, overlap each other at the cell center. Tension applied by the spindle fibers aligns all chromosomes in one plane at the center of the cell.

Spindle fibers shorten, the kinetochores separate, and the chromatids daughter chromosomes are pulled apart and begin moving to the cell poles. The daughter chromosomes arrive at the poles and the spindle fibers that have pulled them apart disappear. The spindle fibers not attached to chromosomes begin breaking down until only that portion of overlap is left.

It is in this region that a contractile ring cleaves the cell into two daughter cells. Microtubules then reorganize into a new cytoskeleton for the return to interphase. Cancer cells reproduce relatively quickly in culture.Gap 0 (G0): There are times when a cell will leave the cycle and quit may be a temporary resting period or more permanent.

The cell cycle and cancer worksheet

An example of the latter is a cell that has reached an end stage of development and will no longer divide (e.g. neuron). This website and its content is subject to our Terms and Conditions. Tes Global Ltd is registered in England (Company No ) with its registered office at 26 Red Lion Square London WC1R 4HQ.

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These assessment tools allow you to evaluate yourself. Ovarian cancer is a cancer that forms in or on an ovary. It results in abnormal cells that have the ability to invade or spread to other parts of the body.

When this process begins, there may be no or only vague symptoms. Symptoms become more noticeable as the cancer progresses. Play a game of Kahoot!

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Animal Cell Mitosis